United sit fourth in the Premier League, 17 points behind local rivals Manchester City, and out of both domestic cup competitions, leaving European glory their only remaining shot at ending a five-year wait to win a trophy.
Yet, not for the first time in the 11 years since the then fresh-faced, skinny Spaniard swapped Madrid for Manchester, De Gea has risen to the challenge of playing in a struggling team.
The fact the 31-year-old has by a distance the most saves of any Premier League goalkeeper this season with 96 is testament to both his form and United’s failure to protect their goal as a team.
De Gea’s stats for outperforming expected goals conceded by nearly 10 goals in 26 games is the best for ‘keepers in Europe’s top five leagues.
A return to the sort of form that earned him United fans’ player of the year four times in five years between 2014 and 2018 looked long gone at the end of last season.
His place even as number one at the club was in danger with Dean Henderson finishing the 2020/21 campaign as the regular starter in the Premier League.
De Gea was retained by then manager Ole Gunnar Solskjaer for the Europa League, but was the only player of the 22 to take a penalty not to score as United lost the final to Villarreal in Gdansk.
Despite that disappointment, there were signs of progress for the Red Devils having finished second to Manchester City in the Premier League.
The enthusiasm generated by the signings of Cristiano Ronaldo, Raphael Varane and Jadon Sancho added to hope of a serious title challenge for the first time since Alex Ferguson retired as manager.